Gallery of Structures Solved in the Lab

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P22 Headful Packaging Nuclease


PDB entry: XXXX
Roy et al., submitted

Human Importin α5 bound to Nup50

PDB entry: 3TJ3
Ruth et al., J. Biol. Chemistry, 2012.

Mammalian Importin α1 bound to PLSCR4 minimal NLS


PDB entry: 3Q5U
Lott et al., J. Biol. Chemistry, 2011

Nonameric small terminase subunit


PDB entry: 3P9A
Roy et al., submitted

Structure of E.coli F1 ATPase inhibited by subunit ε


PDB entry: 3OAA
Cingolani and Duncan, Nat. Struct. Mol. Biol., 2011

Structure of phage Sf6 Tail Needle Knob



PDB entry: 3RWN
Bhardwaj et al., J. Biol. Chemistry, 2011

Full length dodecameric P22 Portal Protein


PDB entry: 3LJ5
Olia et al., Nat. Struct. Mol. Biol., 2011

Dodecameric P22 Portal Protein Core bound to twelve GP4s


PDB entry: 1VT0, 3LJ4
Olia et al., Nat. Struct. Mol. Biol., 2011

An open and closed conformation of Import bound to sIBB-domain


PDB entry: 3LWW
Bhardwaj et al., Biochemistry, 2010

A circular permutant of Barnase


PDB entry: 3DA7
Butler et al., Biochemistry, 2009

Vaccinia Virus Dual-Specificity Phosphatase VH1

PDB entry: 3CM3, 2RF6
Koksal et al., J. Biol. Chemistry, 2009

Phage P22 Tail Needle Gp26


PDB entry: 2POH, 3C9I
Olia et al., Nat. Struct. Mol. Biol., 2007
Olia et al., Protein Sci, 2009

Human Importin β bound to snurportin IBB-domain



PDB entry: 2P8Q, 2Q5D
Mitrousis et al., J. Biol. Chemistry, 2008

Mammalian Importin α bound to Scramblase 1 NLS


PDB entry: 1Y2A
Chen et al., J. Biol. Chemistry, 2005

Human Importin β HEATs (1-11) bound to the PTHrP-NLS(67-94)


PDB entry: 1M5N
Cingolani et al., Molecular Cell, 2002

Human Importin β bound to importin αIBB-domain

PDB entry: 1QGK, 1QGR
Cingolani et al., Nature, 1999